As far as I can tell there is no such feature built into the node. If you want custom offsets per frame, you can do this pretty easily in script. Create an array of offsets that correspond to the frame number, and change it when the frame change is signaled.
This example is a two frame AnimatedSprite.
connect("frame_changed", self, "set_ofs")
var offsets = [Vector2(1000, 1000), Vector2(200, 200)]