The IDE you use will be used only for C# editing and debugging; compiling is handled by the editor as you start up the project. You have to keep the editor open to do other things such as creating and editing scenes.
Thanks. Do you know how can I configure remote debug for Godot? I use MonoDevelop, I see there’s Mono debugging agent option in Godot 3 editor, but I can’t understand how to connect the solution generated by Godot to the engine itself because the solution doesn’t seem runnable.