Thank you for your suggestion. I have already set the 2D pixel snap, and it works fine.
My goal is to make it so animation and positional data in Godot don't use floating point values. For example, normally when making an object move from left to right starting from position 1, the motion would proceed to increment to 1.1, 1.2, 1.3, etc. I want to change the behavior to so the object will move from left to right such that the values will increment from 1 to 2, to 3, and so on. No floating point numbers at all.
I know I probably need to use round() in GDScript, but I am unfamilar with how to get the position of a sprite and change it in such a way that all animation interpolates in whole number integer values.